• Itraconazole ,≥98%(HPLC)
  • G63501 84625-61-6

    Itraconazole

产品订购
产品货号规格货期 优惠价 数量
G63501-100mg 100mg 准现货 询价
  • 产品信息

属性

溶解性 Soluble in chloroform (50 mg/ml), DMF (~0.5 mg/ml), DMSO (50 mM), water (<1 mg/ml at 25 °C), and ethanol (10 mM, with warming).
敏感性 对热敏感
存贮条件 储存温度2-8℃
密度
荧光
IC50
pK Values

描述

别名 亚特那唑;依他康唑;斯皮仁诺;4-[4-[4-[4-[[2-(2,4-二氯苯基)-2-(1H-1,2,4-三唑-1-基甲基)-1,3-二氧戊环-4-基]甲氧基]苯基]-1-哌嗪基]苯基]-2,4-二氢-2-(1-甲基丙基)-3H-1,2,4-三唑-3-酮;伊曲康唑;Oriconazole;R51211;Sporanox
产品介绍 Itraconazole is a triazole antifungal agent. It inhibits the fungal CYP(cytochrome P450) oxidase-mediated synthesis of ergosterol. Itraconazole also acts as an effective hedgehog signaling inhibitor in a Ptch-independent manner, presumably by binding smoothened (Smo) at a site distinct from that targeted by cyclopamine and SAG. Itraconazole is an inhibitor of CYP3A4.
用途 A traizole antifungal agent

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