• Chymostatin TRC
  • D13025 9076-44-2

    Chymostatin

产品订购
产品货号重量货期 优惠价 数量
D13025-100mg 100mg 准现货 询价
D13025-1mg 1mg 准现货 询价
D13025-5mg 5mg 准现货 询价
D13025-10mg 10mg 准现货 询价
D13025-25mg 25mg 准现货 询价
D13025-50mg 50mg 准现货 询价
  • 产品信息

属性

存贮条件 -20℃保存。
密度 1.3400
荧光
IC50
pK Values

描述

别名 胰凝乳蛋白酶抑制剂 ;N-(Nα-Carbonyl-Cpd-X-Phe-al)-Phe (Cpd = capreomycidine) (capreomycidine = [S,S]-α-(2-Iminohexahydro-4-pyrimidyl)glycine)
产品介绍 Chymostatin is a bioactive peptide protease inhibitor that contains chymostatin A as a major form. The compound specifically inhibits chymotrypsin (CTR) (ID50 = 150 ηg/ml), papain (ID50 = 7.5 μg/ml), and cathepsin G along with most cysteine proteases such as cathepsin A, B, H, and L. The compound has been noted as a strong inhibitor of cathepsins A, B, and C. Chymostatin at an effective concentration of 10 to 100 μM weakly inhibits human leukocyte Elastase-1. In rat muscle homogenates chymostatin inhibited the protease cathepsin B and other soluble Ca2+ activated proteases. In the same study, chymostatin decreased protein break down by 20-40% without inhibiting protein production.

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