• 木犀草素,98%
  • C12001 491-70-3

    Luteolin

产品订购
产品货号重量货期 优惠价 数量
C12001-1g 1g 准现货 询价
C12001-250mg 250mg 准现货 询价
C12001-5g 5g 准现货 询价
C12001-25g 25g 准现货 询价
  • 产品信息

属性

溶解性 Soluble in aqueous alkaline solutions (1.4 mg/ml), ethanol (~5 mg/ml), DMSO (7 mg/ml), 1eq. NaOH (5 mM), DMF (~20 mg/ml), 1:5 solution of DMF:PBS(pH7.2) (`~1 mg/ml), water (1 mg/ml) at 25 °C, and methanol.
存贮条件 贮存温度2-8℃
熔点 330°C
密度 1.6540
荧光
IC50
pK Values

描述

别名 3‘,4‘,5,7-四羟基黄酮;檞片素;3‘,4‘,5,7-Tetrahydroxyflavone
产品介绍 Luteolin is an antioxidant flavonoid and a free radical scavenger. It inhibits rat liver cytosolic glutathione S-transferase activity and soybean and reticulocyte 15-LO (15-lipoxygenases). Luteolin also shows cytotoxic effects on Raji lymphoma cells. Incubation of the non-tumor cell line C3H10T?CL8 with luteolin results in induction of p53 accumulation and apoptosis, with apoptosis occurring at the G2/M phase of the cell cycle. Luteolin is an inhibitor of Cot, PDE1-5, c-Src, HDAC, Maltase-glucoamylase, Topo I, PKC ε, Fatty Acid Synthase, PPAR γ and MMP.
用途 An inhibitor of glutathione S-transferase and 15-LO.

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